Journal: Frontiers in Neural Circuits

Article Title: Long-term Potentiation at Temporoammonic Path-CA1 Synapses in Freely Moving Rats

doi: 10.3389/fncir.2016.00002

Figure Lengend Snippet: mTAP-CA1 synapses and putative population spikes exhibit an enduring form of long-term potentiation (LTP) in freely moving rats. (A) Daily mTAP-CA1 (•, n = 6) and cCA3-CA1 (°, n = 6) slope analysis. Inset: baseline (solid line) and post-TBS (dashed line) mTAP-CA1 responses. Calibration: 0.5 mV, 5 ms. Three out of six animals exhibited heterosynaptic long-term depression following TBS of the medial TAP. (B) Curve fitting of post LTP daily slope averages indicate mTAP-CA1 LTP decay ( n = 6) is represented as a sum of two exponential curves with time constants (τ) of 2.7 days and 148 days to decay 63.2% of maximal LTP. (C) Daily mTAP-CA1 putative population spike amplitude analysis in animals that exhibited population spike potentiation following TBS ( n = 4). Significant differences between post- and pre-tetanus putative population spike amplitudes persist for 5 days after LTP induction [* p < 0.05, repeated measures one way ANOVA]. Inset: baseline (solid line) and post-TBS (dashed line) mTAP-CA1 responses. Calibration: 0.5 mV, 5 ms. (D) Curve fitting of post LTP daily mTAP-CA1 putative population spike amplitude averages indicates population spike potentiation decays exponentially with a time constant (τ) of 9.6 days to decay 63.2% of maximal LTP.

Article Snippet: Averaged daily data were plotted with an exponential curve fit (SigmaPlot 12, Systat Software, San Jose, CA, USA) to determine the LTP decay time constant (τ), defined as the time of decaying 63.2% of maximal LTP.

Techniques:

Journal: Membranes

Article Title: An Assessment on Average Pressure Drop and Dust-Holding Capacity of Hollow-Fiber Membranes in Air Filtration

doi: 10.3390/membranes11070467

Figure Lengend Snippet: Dust loading curves fitted with different models: ( a ) various membranes and velocities at a constant loading rate of 4 g/h with exponential fit (the minor x -axis in red is for P60, at 40 cm/s), ( b ) the same fitted with 4th order polynomial (the minor x -axis in red is for P60, at 40 cm/s), ( c ) P80 membrane at 20 cm/s at different loading rates with exponential fit, ( d ) the same fitted with 4th order polynomial.

Article Snippet: The data obtained for this membrane was thus possible to approximate using the exponential curve fit, which is generally done in the ASHRAE dust-holding capacity test [ ] and which was previously used in several studies [ , ].

Techniques: Membrane

Journal: Membranes

Article Title: An Assessment on Average Pressure Drop and Dust-Holding Capacity of Hollow-Fiber Membranes in Air Filtration

doi: 10.3390/membranes11070467

Figure Lengend Snippet: Dust-holding capacity per cake pressure drop of different membranes at different permeate velocities at a constant loading rate of 4 g/h ( a ) and P80 membrane at 20 cm/s at different loading rates ( b ), DHC measured ( DHC meas ), DHC from exponential fit ( DHC exp ) and DHC from polynomial fit ( DHC pol ) are at the major axis, DHC theoretical ( DHC theor ) is at the minor axis.

Article Snippet: The data obtained for this membrane was thus possible to approximate using the exponential curve fit, which is generally done in the ASHRAE dust-holding capacity test [ ] and which was previously used in several studies [ , ].

Techniques: Membrane

Journal: Oncotarget

Article Title: Potential independent action of sigma receptor ligands through inhibition of the Kv2.1 channel

doi: 10.18632/oncotarget.19581

Figure Lengend Snippet: (A) Representative current traces from a cell expressing Kv2.1 channel before (HR; black trace) and during treatment with σ1-R receptor agonist PRE084 (10 μM, red trace). Inset voltage pulse to 50 mV from a holding potential of -60 mV. (B) Representative Kv2.1 channel current traces from a cell treated with σ1-R antagonist BD1047 (50 μM, red trace) compared to total current (black trace). (C) Comparison of Kv2.1 current traces before (HR, black trace) and during treatment with σ1-R antagonist NE100 (50 μM, red trace). (D) Time course of current amplitude at +60 mV. Recordings during Pre84 treatment is represented as red filled circles. (E) Filled circles (red) showing current amplitude time course during treatment of Kv2.1 expressing cells with BD1047. (F) Kv2.1 outward current amplitude as in D in presence of NE100 (50 μM, red filled circles). Both in E and F the solid line represents single exponential curve fit. (G) Average Kv2.1 whole-cell normalized current-voltage plot obtained in control solution (black squares) and during application of Pre084. (H) Comparison of average normalized current-voltage curve in presence of control bath solution and BD1047. (I) Average normalized current-voltage curve determined in control solution (black squares) and NE100 (red circles). (J) The G-V relationships of the control (solid black square), and in presence of BD1047 (blue triangle) or NE100 (red circle) are illustrated. (K) Normalized G-V curves as in J were fitted with the Boltzmann function. Data points in G-K are mean ± SEM (n=5). * P < 0.05 compared to control.

Article Snippet: We used 1 st order exponential nonlinear curve fitting equation; for the time course data y = A 1 * exp ( − x t 1 ) + y 0 to determine inhibition time constant in Origin (Origin Lab, Northampton, MA).

Techniques: Expressing, Comparison, Control